Core Facilities - JANUS Automated Workstation
Location: Biosciences Screening Core
Person responsible: Enda O'Connell
Phone: +353 91 495435
The Perkin Elmer Janus Automated Workstation is designed to efficiently automate liquid handling and detection procedures.
- Drug Discovery & Characterisation (e.g. Compound library screening, IC50),
- Cellular Assays (e.g. Proliferation, Cytotoxicity, RNAi),
- Enzymatic Assays (e.g. Kinases, Transferases)
- Binding Assays (e.g. ELISA, GTP, cAMP)
- Molecular Biology (e.g. Reporter Genes, PCR, DNA Normalisation)
- Sample Analysis (e.g. Environmental, Food, Forensics)
Liquid transfers are performed from a range of microplates, tubes and troughs, by 96-tip and 8-tip flexible, low volume pipetting arms, enabling:
- Compound library management,
- Sample preparation,
- Plate replication and reformatting,
- Intra- and Inter-plate serial dilution,
- Target cherry picking,
- Mixing, stacking, barcode reading.
The integrated Victor X5 Multilabel Reader has a wide range of detection methods:
- Time-resolved Fluorometry,
- Fluorescence Polarisation.
To enable sterile, cell-based assays to be safely performed, the Janus Workstation is housed in a BigNeat Class II Biosafety cabinet.